New research on obesity
A few months ago, I wondered if it were possible that the amount of calories absorbed from food could vary from person to person. In fact, recent research has shown that not only is caloric absorption likely to vary from person to person, but can vary over time for one person.
When I wrote my blog post, I didn’t have any idea what could cause the variation. I figured it was something about our bodies themselves. As it turns out, bacteria that thrive in our intestines likely cause significant variations in the amount of calories we can extract from food. Of course the research is still new, and it was done on mice, but it still looks very promising.
Biologist Jeffrey Gordon of Washington University in St. Louis became quite well known a few years ago for a group of very skinny mice in his lab. The mice were skinny because they had no bacteria in their intestines. Gordon had kept them completely bacteria-free. If a bacteria-free mouse eats, food passes right through the intestine, significantly undigested.
So without bacteria, the mouse can eat and eat and eat and never gain weight. But when Gordon exposed the mice to “this big, bad, dirty world,” as Gibson calls it, the mice suddenly turned their food into more calories and gained weight. So bacteria matter. Apparently, they can digest food far more efficiently.
So researchers now are focusing on learning more about the 500+ species of bacteria that live in our guts and what impact they have on all kinds of stuff in addition to digestive efficiency: “stomach ulcers, … asthma, hay fever, allergies and eczema”. It is entirely possible that an anti-biotic could be developed to kill some of the more efficient food digesters, allowing food to pass through less digested, and allowing the person to lose weight while eating full meals. It really could be the magic weight-loss pill so many have been seeking.